Dr. Adam MacLean works with Prof. Qing Nie in the Department of Mathematics. His research focuses on developing mathematical and statistical models to study molecular signaling pathways, particularly those that control stem cell dynamics and cell fate decisions. Adam collaborates closely with cell and molecular biologists at UCI, where they are investigating how robust epithelial phenotypes (such as skin/hair regeneration) are maintained, and how the stem cell pathways responsible become misregulated when cancers arise.
Adam received his Ph.D. from Imperial College London where he developed dynamical models and methods for statistical inference to study the importance of ecological interactions as drivers of leukemia in hematopoietic stem cell niche. He recently presented his work at the 2016 UCI Research Symposium with a poster presentation.